The Deadly Sin uses a high Deadly Arts attribute to inflict conditions on your target and other skills to exploit those conditions.

Attributes and Skills

Assassin / Any	Attribute Rank
Dagger Mastery	10+2
Critical Strikes	8+2
Shadow Arts	6+2
Deadly Arts	11+1

Crippling Dagger

Jagged Strike

Entangling Asp

Jungle Strike

Blinding Powder

Shadow Refuge

Seeping Wound

Signet of Shadows

Equipment

• Armor doesn't really matter except nightstalker because you will be attacking less than normal.
• No zealous or vampiric daggers (same reason), use barbed, poisonous, or crippling daggers mods.

Usage

• This build can deal a lot of damage, especially over time but there is a heavy cooldown and energy cost.
• Use Crippling Dagger on your target foe, then follow up with Jagged Strike to cover the cripple condition with a bleed.
• Use Entangling Asp -> Jungle Strike and Seeping Wound to add extra health degen.
• Afterwards, use Blinding Powder and Signet of Shadows.
• If you receive too much damage and have no monk ally nearby, don't hesitate to cripple your target and run. It could save your life and it's obviously much better than dying.

Counters

• Condition removal or transfer (Plague Touch)
• This build has no real escape ability
• The normal melee counters (Empathy)

Variants

• If you replace Seeping Wound with Assassin's Promise, the PvP build becomes a good PvE build vs groups of weaker creatures.
• You can replace Signet of Shadows with a dual attack (Twisting Fangs to lengthen the Bleeding and add Deep Wound on top of all the other conditions)